2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
304896-28-4
434.3
C23H13Cl2N3O2
DMF, DMSO
-20°C
AGK2 is a potent inhibitor of sirtuin 2 (SIRT2) (IC= 3.5 M). AGK2 is 15-fold more selective for SIRT2 than SIRT1 and SIRt3. Inhibition of SIRT2 rescued synuclein toxicity and modified inclusion morphology in a cellular model of Parkinsons disease.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
